Unified rhombic lip origins of group 3 and group 4 medulloblastoma

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

Visualization of macrophage subsets in the development of the fetal human inner ear

Interactive 3D brain models now available

Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration

Interactive 3D embryo models.

CD34+CD19−CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cell differentiation

NEW: SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile

HDBR @ Genetics Society Genetics of Reproduction Conference

Patient Experience Survey Results

Mapping the developing human cardiac endothelium at single-cell resolution identifies MECOM as a regulator of arteriovenous gene expression

HDBR @ Organoid Research Day

Tyramide signal amplification coupled with multiple immunolabeling and RNAScope in situ hybridization in formaldehyde-fixed paraffin-embedded human fetal brain

Single-cell roadmap of human gonadal development

Interactive Heart Models

Cells of the human intestinal tract mapped across space and time

Development of a physiological model of human middle ear epithelium

HDBR Abnormal Fetal Samples Exome Sequencing Data

The need for a standard for informed consent for collection of human fetal material

Featured resource: the Node (The Company of Biologists)

Human Developmental Biology Resource (HDBR) Atlas

CS16 Interactive Heart Reconstruction

Rescuing human fetal tissue research in the United States: A call for additional regulatory reform

A roadmap for the Human Developmental Cell Atlas

ZSWIM7 Is Associated With Human Female Meiosis and Familial Primary Ovarian Insufficiency

Protein expression in the developing spinal cord

Interactive models of early heart development

HDBR Publications

Image Data Resource - update

Second dataset uploaded to the Image Data Resource

HDBR Atlas – digital downloads.

Spatial and cell type transcriptional landscape of human cerebellar development

Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface

Therapeutic Potential of Niche-Specific Mesenchymal Stromal Cells for Spinal Cord Injury Repair

Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features.

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis.

Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia.

HDBR Atlas – Gene expression in the developing spinal cord

Gene Expression in the Developing Spinal Cord

Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development

Gene expression in the developing eye

Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset

HDBR gene expression data now available in the Image Data Resource

Identification of a Primary Stroma and Novel Endothelial Cell Projections in the Developing Human Cornea

Selective Expression of Nicotinic Receptor Sub-unit mRNA in Early Human Fetal Forebrain